hrp0089p2-p052 | Bone, Growth Plate & Mineral Metabolism P2 | ESPE2018

Evaluation of Bone Mineral Density in a Cohort of Children with Growth Hormone Deficiency

Cenciarelli Valentina , Bruzzi Patrizia , Predieri Barbara , Cerbone Caterina , Madeo Simona , Leo Francesco

Background: Growth Hormone (GH) plays an important role in linear growth and in bone turnover during childhood. GH deficiency (GHD) may cause secondary osteoporosis associated to low bone mineral density (BMD), impairment of bone turnover and increased fracture rate. The effects of treatment with recombinant human Growth Hormone (rhGH) on bone metabolism are controversial. We aimed to assess BMD using dual energy x-ray absorptiometry (DEXA) among a cohort of children with GHD ...